Modifications of single acetylcholine-activated channels in BC3H-1 cells. Effects of trimethyloxonium and pH.
نویسندگان
چکیده
منابع مشابه
Modifications of Single Acetylcholine-activated Channels BC3H-1 Cells in Effects of Trimethyloxonium and pH
We have examined the effects o f chemical modification with tr imethyloxonium (TMO) and changes in external p H on the proper t ies o f acetylcholine (ACh)-activated channels in BC3H-1 cells, a clonal muscle cell line. TMO reacts covalently and specifically with carboxylic acid moieties in proteins to convert them to neutral methyl esters. In BC3H-1 cells TMO modification reduces the whole-cell...
متن کاملModifications of single acetylcholine-activated channels in BC3H-1 cells. Effects of trimethyloxonium and pH
We have examined the effects of chemical modification with trimethyloxonium (TMO) and changes in external pH on the properties of acetylcholine (ACh)-activated channels in BC3H-1 cells, a clonal muscle cell line. TMO reacts covalently and specifically with carboxylic acid moieties in proteins to convert them to neutral methyl esters. In BC3H-1 cells TMO modification reduces the whole-cell respo...
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ژورنال
عنوان ژورنال: Journal of General Physiology
سال: 1990
ISSN: 0022-1295,1540-7748
DOI: 10.1085/jgp.96.1.1